Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HTR1B | P28222 | 2/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | NSD2 | O96028 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8713585 | 1.00 | MEN1 (0.47) | MEN1KMT2AHTR1BHTR1DKDM4E | |
| SCHEMBL8713603 | 0.89 | SLC2A1 (0.42) | MEN1KMT2AKDM4ENSD2ALDH1A1 | |
| SCHEMBL8713605 | 0.89 | SLC2A1 (0.42) | MEN1KMT2AKDM4ENSD2ALDH1A1 | |
| SCHEMBL8720156 | 0.82 | TAAR1 (0.60) | MEN1KMT2AKDM4EALDH1A1ADRA1A | |
| SCHEMBL8720159 | 0.82 | TAAR1 (0.60) | MEN1KMT2AKDM4EALDH1A1ADRA1A | |
| SCHEMBL7147259 | 0.78 | ADRB2 (0.56) | ADRA1DADRA1AADRA1BSIGMAR1 | |
| SCHEMBL7147255 | 0.78 | ADRB2 (0.56) | ADRA1DADRA1AADRA1BSIGMAR1 | |
| SCHEMBL8714017 | 0.76 | CYP2D6 (0.58) | KDM4EALDH1A1SIGMAR1TAAR1LMNA | |
| SCHEMBL8714019 | 0.76 | CYP2D6 (0.58) | KDM4EALDH1A1SIGMAR1TAAR1LMNA | |
| SCHEMBL8713927 | 0.76 | ADRA2A (0.49) | KDM4EALDH1A1ADRA1ASIGMAR1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |