⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16287681 | 0.87 | — | — | |
| SCHEMBL28162402 | 0.82 | TRPM8 (0.30) | — | |
| SCHEMBL19163726 | 0.80 | — | — | |
| Bicarbonate SCHEMBL874121 | 0.78 | CA2 (0.38) | — | |
| SCHEMBL4448679 | 0.77 | DNM1 (0.36) | — | |
| SCHEMBL378172 | 0.76 | — | — | |
| SCHEMBL28681827 | 0.75 | — | — | |
| SCHEMBL19175930 | 0.75 | TSHR (0.32) | — | |
| SCHEMBL16630535 | 0.75 | — | — | |
| SCHEMBL30410125 | 0.73 | LMNA (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192534-A1 | CYCLIN-DEPENDENT KINASE 9 (CDK9) DEGRADERS AND METHODS OF USING THEREOF | OHIO STATE INNOVATION FOUNDATION (US) | 2023-10-05 | — | — | WO | disclosed |
| EP-0476640-B1 | High performance tire treads and tires | BRIDGESTONE CORP (JP) | 1998-02-04 | — | — | EP | disclosed |
| EP-0476663-B1 | Polymetalated 1-alkyne compositions | BRIDGESTONE CORP (JP) | 1997-04-23 | — | — | EP | disclosed |
| EP-0491199-B1 | Continuous process for preparing copolymers of conjugated dienes and aromatic vinyl compounds | BRIDGESTONE CORP (JP) | 1996-06-05 | — | — | EP | disclosed |
| US-5489660-A | HIGH MOLECULAR WEIGHT ADDITION POLYMERS MADE BY USING TRI-METALLIZED 1-ALKYNES AS POLYMERIZATION CATALYSTS | BRIDGESTONE CORPORATION (JP) | 1996-02-06 | — | — | US | disclosed |
| EP-0476665-B1 | Oil extended ultra high molecular weight elastomers | BRIDGESTONE CORP (JP) | 1995-12-06 | — | — | EP | disclosed |
| EP-0476641-B1 | Ultra high molecular weight elastomer composition | BRIDGESTONE CORP (JP) | 1995-11-08 | — | — | EP | disclosed |
| EP-0476662-B1 | Ultra high molecular weight copolymers of conjugated dienes and aromatic vinyl compounds | BRIDGESTONE FIRESTONE INC (US) | 1995-11-08 | — | — | EP | disclosed |
| EP-0491229-B1 | Pneumatic tires for heavy-load vehicles | BRIDGESTONE CORP (JP) | 1995-05-24 | — | — | EP | disclosed |
| US-5331036-A | Made with trimetalated 1-alkyne catalyst | BRIDGESTONE CORPORATION (JP) | 1994-07-19 | — | — | US | disclosed |
| US-5231152-A | Catalytic polymerization using organometallic compound catalyst | BRIDGESTONE CORPORATION (JP) | 1993-07-27 | — | — | US | disclosed |
| US-5147951-A | Using trimetallated 1-alkylne catalyst | BRIDGESTONE/FIRESTONE, INC. (US) | 1992-09-15 | — | — | US | disclosed |
| EP-0491229-A1 | Pneumatic tires for heavy-load vehicles | Bridgestone Corporation (JP) | 1992-06-24 | — | — | EP | disclosed |
| EP-0491199-A1 | Continuous process for preparing copolymers of conjugated dienes and aromatic vinyl compounds | Bridgestone Corporation (JP) | 1992-06-24 | — | — | EP | disclosed |
| EP-0476640-A1 | High performance tire treads and tires | Bridgestone Corporation (JP) | 1992-03-25 | — | — | EP | disclosed |
| EP-0476663-A1 | Polymetalated 1-alkyne compositions | Bridgestone Corporation (JP) | 1992-03-25 | — | — | EP | disclosed |
| EP-0476665-A1 | Oil extended ultra high molecular weight elastomers | BRIDGESTONE CORPORATION (JP) | 1992-03-25 | — | — | EP | disclosed |
| EP-0476641-A1 | Ultra high molecular weight elastomer composition | BRIDGESTONE CORPORATION (JP) | 1992-03-25 | — | — | EP | disclosed |
| EP-0476662-A1 | Ultra high molecular weight copolymers of conjugated dienes and aromatic vinyl compounds | BRIDGESTONE/FIRESTONE, INC. (US) | 1992-03-25 | — | — | EP | disclosed |
| US-5080835-A | Anionic polymerization catalysts | BRIDGESTONE/FIRESTONE, INC. (US) | 1992-01-14 | — | — | US | disclosed |