Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 4/20 | 0.36 |
| ▸ | HTR2C | P28335 | 3/20 | 0.36 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | HTR7 | P34969 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8718452 | 0.83 | ADRB1 (0.44) | SIGMAR1ADRB1HTR3AALDH1A1MEN1 | |
| SCHEMBL27418984 | 0.81 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2APOLBTSHR | |
| SCHEMBL5774546 | 0.79 | KMT2A (0.43) | ALDH1A1MEN1KMT2APOLBTSHR | |
| SCHEMBL8715074 | 0.76 | PLD1 (0.45) | ALDH1A1MEN1KMT2AHTR6USP2 | |
| SCHEMBL8719888 | 0.73 | MAPT (0.31) | SIGMAR1ADRB1HTR3EHTR3BHTR3A | |
| SCHEMBL8716758 | 0.73 | ADRB1 (0.32) | SIGMAR1ADRB1HTR3EHTR3BHTR3A | |
| SCHEMBL736136 | 0.72 | SIGMAR1 (0.46) | SIGMAR1ADRB1HTR3EHTR3BHTR3A | |
| SCHEMBL21906494 | 0.72 | SIGMAR1 (0.45) | SIGMAR1ADRB1HTR3EHTR3BHTR3A | |
| SCHEMBL27620685 | 0.72 | SIGMAR1 (0.45) | SIGMAR1ADRB1HTR3EHTR3BHTR3A | |
| SCHEMBL28228488 | 0.72 | SIGMAR1 (0.45) | SIGMAR1ADRB1HTR3EHTR3BHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0822939-A1 | CYCLIC PENTAPEPTIDE LH-RH RECEPTOR ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 1998-02-11 | — | — | EP | disclosed |
| WO-1996034012-A1 | CYCLIC PENTAPEPTIDE LH-RH RECEPTOR ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-10-31 | — | — | WO | disclosed |