Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 8/20 | 0.41 |
| ▸ | CNR2 | P34972 | 8/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 6/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 6/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8708320 | 0.86 | HSD17B1 (0.42) | NPC1LMNACASP3RAB9ASENP8 | |
| SCHEMBL31215161 | 0.76 | LMNA (0.44) | MAPK1SMN1; SMN2NPC1LMNACASP3 | |
| SCHEMBL825377 | 0.76 | LMNA (0.44) | MAPK1SMN1; SMN2NPC1LMNACASP3 | |
| SCHEMBL28873360 | 0.76 | MAPK1 (0.44) | MAPK1SMN1; SMN2NPC1LMNACASP3 | |
| SCHEMBL8707495 | 0.75 | PTPN5 (0.48) | LMNAHSD17B1HSD17B2CYP3A4CYP2C9 | |
| SCHEMBL1239911 | 0.73 | ALDH1A1 (0.53) | MAPK1SMN1; SMN2NPC1LMNACASP3 | |
| SCHEMBL6563046 | 0.72 | CA12 (0.50) | HSD17B1HSD17B2 | |
| SCHEMBL6886222 | 0.72 | CA12 (0.47) | NPC1RAB9AHSD17B2 | |
| SCHEMBL25387140 | 0.72 | ALDH1A1 (0.44) | SMN1; SMN2NPC1LMNACASP3RAB9A | |
| SCHEMBL4887812 | 0.71 | CNR1 (0.77) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723500-A | WATER INSOLUBLE, NONCATIONIC, ANTIBACTERIAL, STERICALLY HINDERED PHENOL; MOUTHWASHES, DENTIFRICES | COLGATE-PALMOLIVE COMPANY (US) | 1998-03-03 | — | — | US | claimed |
| US-5723500-A | WATER INSOLUBLE, NONCATIONIC, ANTIBACTERIAL, STERICALLY HINDERED PHENOL; MOUTHWASHES, DENTIFRICES | COLGATE-PALMOLIVE COMPANY (US) | 1998-03-03 | — | — | US | disclosed |