Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8714022 | 0.89 | SIGMAR1 (0.43) | SIGMAR1POLBMAPK1ADRA2BADRA2C | |
| SCHEMBL8714374 | 0.82 | SIGMAR1 (0.38) | SIGMAR1MAPK1ADRA2BADRA2CSLC6A2 | |
| SCHEMBL8430263 | 0.80 | SIGMAR1 (0.50) | SIGMAR1MAPK1ADRA2BADRA2CSLC6A2 | |
| SCHEMBL8713645 | 0.80 | SIGMAR1 (0.44) | SIGMAR1ADRB2MAPK1ADRA2BADRA2C | |
| SCHEMBL8718550 | 0.79 | HDAC1 (0.45) | SIGMAR1POLBMAPK1 | |
| SCHEMBL8713719 | 0.79 | MAPT (0.42) | BCL2L1 | |
| SCHEMBL8718156 | 0.77 | SIGMAR1 (0.42) | SIGMAR1ADRA2BADRA2CSLC6A2HTR2A | |
| SCHEMBL8716243 | 0.77 | ACHE (0.46) | SIGMAR1ADRB2POLBADRA2BADRA2C | |
| SCHEMBL8713177 | 0.77 | SIGMAR1 (0.40) | SIGMAR1MAPK1ADRA2BADRA2CSLC6A2 | |
| SCHEMBL8714206 | 0.77 | SIGMAR1 (0.44) | SIGMAR1PSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |