Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 3/20 | 0.41 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8714022 | 0.83 | SIGMAR1 (0.43) | MAPTTSHRLMNARAB9AMEN1 | |
| SCHEMBL8718550 | 0.80 | HDAC1 (0.45) | MAPTTSHRLMNAMEN1KMT2A | |
| SCHEMBL8714181 | 0.79 | SIGMAR1 (0.40) | BCL2L1 | |
| SCHEMBL8714374 | 0.77 | SIGMAR1 (0.38) | TSHRCYP3A4KDM4E | |
| SCHEMBL8716243 | 0.76 | ACHE (0.46) | TSHRKMT2ACYP3A4ALOX15ALDH1A1 | |
| SCHEMBL8717324 | 0.75 | ALDH1A1 (0.44) | MAPTTSHRRAB9AMEN1KMT2A | |
| SCHEMBL8430263 | 0.75 | SIGMAR1 (0.50) | TSHRKDM4E | |
| SCHEMBL8713645 | 0.74 | SIGMAR1 (0.44) | TSHRKDM4E | |
| SCHEMBL8718156 | 0.72 | SIGMAR1 (0.42) | RAB9ANPC1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8719319 | 0.72 | SLC7A5 (0.45) | TSHRLMNAMEN1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |