Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PHPT1 | Q9NRX4 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8717324 | 0.86 | ALDH1A1 (0.44) | HDAC1KDM4ESMN1; SMN2POLBKMT2A | |
| SCHEMBL8714022 | 0.83 | SIGMAR1 (0.43) | KDM4ELMNAPOLBKMT2AMEN1 | |
| SCHEMBL8713719 | 0.80 | MAPT (0.42) | KDM4ELMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL8714181 | 0.79 | SIGMAR1 (0.40) | POLBMAPK1SIGMAR1 | |
| SCHEMBL8714374 | 0.77 | SIGMAR1 (0.38) | KDM4ECYP3A4TSHRMAPK1SIGMAR1 | |
| SCHEMBL8430263 | 0.75 | SIGMAR1 (0.50) | KDM4ETSHRADORA2AADORA1MAPK1 | |
| SCHEMBL8713645 | 0.74 | SIGMAR1 (0.44) | KDM4ETSHRMAPK1SIGMAR1 | |
| SCHEMBL8718156 | 0.72 | SIGMAR1 (0.42) | KDM4EKMT2AALDH1A1ADORA2AADORA1 | |
| SCHEMBL8713177 | 0.72 | SIGMAR1 (0.40) | KDM4EGAAMAPTTSHRMAPK1 | |
| SCHEMBL8716243 | 0.72 | ACHE (0.46) | POLBKMT2AALDH1A1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |