Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8717467 | 0.87 | MEN1 (0.48) | CYP3A4CYP2D6LMNAMEN1KMT2A | |
| SCHEMBL8718275 | 0.87 | KIF11 (0.37) | KCNH2SLC6A4CYP3A4CYP2D6SLC6A2 | |
| SCHEMBL8720152 | 0.86 | MEN1 (0.39) | KCNH2SLC6A4CYP3A4CYP2D6SLC6A2 | |
| SCHEMBL8717503 | 0.84 | CBX7 (0.37) | KCNH2SLC6A4CYP3A4CYP2D6SLC6A2 | |
| SCHEMBL8720042 | 0.84 | IDO1 (0.41) | SLC6A2LMNAMEN1KMT2AIDO1 | |
| SCHEMBL8713551 | 0.83 | KIF11 (0.38) | CYP3A4CYP2D6LMNAMEN1KMT2A | |
| SCHEMBL8717145 | 0.82 | SMN1; SMN2 (0.40) | LMNAMEN1KMT2ANPC1RAB9A | |
| SCHEMBL8719259 | 0.82 | NR3C1 (0.39) | CYP3A4CYP2D6LMNAMEN1KMT2A | |
| SCHEMBL8715312 | 0.82 | MEN1 (0.41) | KCNH2LMNAMEN1KMT2ANR3C1 | |
| SCHEMBL8718432 | 0.81 | LMNA (0.40) | KCNH2LMNAMEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |