Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8720042 | 0.90 | IDO1 (0.41) | MEN1KMT2AIDO1TAAR1MAPT | |
| SCHEMBL8719228 | 0.89 | MAPT (0.44) | MC4RCSNK1DMAPTGAANR3C1 | |
| SCHEMBL8713551 | 0.89 | KIF11 (0.38) | MEN1KMT2AIDO1TAAR1MAPT | |
| SCHEMBL8717467 | 0.88 | MEN1 (0.48) | MEN1KMT2AIDO1TAAR1MAPT | |
| SCHEMBL8713638 | 0.83 | MEN1 (0.35) | MEN1KMT2AKCNH2TAAR1MAPT | |
| SCHEMBL8716358 | 0.82 | GRIN2B (0.46) | CACNA1GKCNH2MC4RCSNK1DNR3C1 | |
| SCHEMBL8714402 | 0.82 | KCNH2 (0.38) | MEN1KMT2AKCNH2IDO1TAAR1 | |
| SCHEMBL8716180 | 0.82 | IDO1 (0.41) | MEN1KMT2AIDO1TAAR1MAPT | |
| SCHEMBL8720320 | 0.81 | NR3C1 (0.41) | MEN1KMT2AKCNH2IDO1TAAR1 | |
| SCHEMBL8717145 | 0.81 | SMN1; SMN2 (0.40) | MEN1KMT2AIDO1TAAR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |