Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 1/20 | 0.56 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 3/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | HTR7 | P34969 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8713391 | 0.88 | AVPR2 (0.53) | AVPR2AVPR1AHTR1ADRD2HTR7 | |
| SCHEMBL8722757 | 0.84 | DRD2 (0.65) | AVPR2AVPR1AHTR1ADRD2HTR7 | |
| SCHEMBL8902187 | 0.83 | HTR1A (0.67) | AVPR2AVPR1AHTR1ADRD2HTR7 | |
| SCHEMBL8901177 | 0.83 | HTR1A (0.67) | AVPR2AVPR1AHTR1ADRD2HTR7 | |
| SCHEMBL8724506 | 0.83 | HTR1A (0.67) | AVPR2AVPR1AHTR1ADRD2HTR7 | |
| SCHEMBL8894896 | 0.81 | ALDH1A1 (0.57) | AVPR2AVPR1AHTR1ADRD2HTR7 | |
| SCHEMBL8717040 | 0.81 | AVPR2 (0.49) | AVPR2AVPR1AHTR1ADRD2HTR7 | |
| SCHEMBL8722874 | 0.81 | AVPR2 (0.58) | AVPR2AVPR1AHTR1ADRD2HTR7 | |
| SCHEMBL8720267 | 0.81 | AVPR2 (0.58) | AVPR2AVPR1AHTR1ADRD2HTR7 | |
| SCHEMBL8722383 | 0.81 | HTR1A (0.58) | AVPR2AVPR1AHTR1ADRD2HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998031669-A1 | NOVEL ARYLPIPERAZINE DERIVED FROM PIPERIDINE AS ANTIDEPRESSANT MEDICINES | PIERRE FABRE MEDICAMENT (FR) | 1998-07-23 | — | — | WO | disclosed |