Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 5/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.65 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.65 |
| ▸ | MLYCD | O95822 | 1/20 | 0.61 |
| ▸ | NAMPT | P43490 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.59 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.59 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.59 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | AHR | P35869 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | CASP3 | P42574 | 1/20 | 0.57 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8716774 | 0.86 | MLYCD (0.64) | HDAC1HDAC6HDAC11MLYCDNAMPT | |
| SCHEMBL8710976 | 0.84 | MEN1 (0.63) | HDAC1HDAC6HDAC11MLYCDNAMPT | |
| SCHEMBL8716505 | 0.84 | KMT2A (0.65) | HDAC1HDAC6HDAC11MLYCDPOLB | |
| Hydrochloric Acid SCHEMBL10695546 | 0.82 | HDAC1 (0.65) | HDAC1HDAC6HDAC11MLYCDNAMPT | |
| SCHEMBL8710838 | 0.82 | HDAC1 (0.62) | HDAC1HDAC6HDAC11MLYCDNAMPT | |
| SCHEMBL29989592 | 0.82 | RAB9A (0.77) | HDAC1HDAC6MLYCDPABPC1APOBEC3A | |
| SCHEMBL527994 | 0.82 | RAB9A (0.77) | HDAC1HDAC6MLYCDPABPC1APOBEC3A | |
| SCHEMBL9620772 | 0.81 | F10 (0.81) | HDAC1HDAC6HDAC11MLYCDPABPC1 | |
| SCHEMBL8970971 | 0.81 | POLB (0.70) | MLYCDPOLBPABPC1APOBEC3AEIF4H | |
| SCHEMBL9620767 | 0.81 | MLYCD (0.69) | HDAC1MLYCDPOLBPABPC1APOBEC3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5728835-A | HYPOTENSIVE AGENTS; ANTIISCHEMIC AGENTS | TOA EIYO, LTD. (JP) | 1998-03-17 | — | — | US | disclosed |
| EP-0661266-A1 | Substituted cyclic amine compounds as 5HT2 antagonists | TOA EIYO LTD. (JP) | 1995-07-05 | — | — | EP | disclosed |