SCHEMBL8714933

SCHEMBL8714933

O=C(O)CN1CCN(CC(=O)O)CCN(Cc2cc([N+](=O)[O-])ccc2O)CCN(CC(=O)O)CC1

nearest known ligand 0.71

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CTSB P07858 1/20 0.68
ALDH1A1 P00352 7/20 0.49
KDM4E B2RXH2 6/20 0.49
LMNA P02545 3/20 0.49
SMN1; SMN2 Q16637 6/20 0.48
NOX4 Q9NPH5 1/20 0.47
BACE1 P56817 1/20 0.46
HTT P42858 1/20 0.45
MAPK1 P28482 3/20 0.44
MAPT P10636 2/20 0.44
POLB P06746 2/20 0.44
NPSR1 Q6W5P4 1/20 0.44
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
NPC1 O15118 1/20 0.43
NR2F2 P24468 1/20 0.43
RAB9A P51151 1/20 0.43
DRD4 P21917 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21044045 1.00 CTSB (0.68) CTSBALDH1A1KDM4ELMNASMN1; SMN2
SCHEMBL21044031 0.93 CTSB (0.60) CTSBALDH1A1KDM4ELMNASMN1; SMN2
SCHEMBL21043999 0.93 CTSB (0.60) CTSBALDH1A1KDM4ELMNASMN1; SMN2
SCHEMBL9120399 0.88 CTSB (0.54) CTSBALDH1A1KDM4ELMNASMN1; SMN2
SCHEMBL9120415 0.88 CTSB (0.54) CTSBALDH1A1KDM4ELMNASMN1; SMN2
SCHEMBL28441625 0.87 ALDH1A1 (0.55) CTSBALDH1A1KDM4ELMNASMN1; SMN2
SCHEMBL30218415 0.86 CTSB (0.53) CTSBALDH1A1KDM4ELMNASMN1; SMN2
SCHEMBL21043963 0.86 CTSB (0.53) CTSBALDH1A1KDM4ELMNASMN1; SMN2
SCHEMBL30218432 0.85 CTSB (0.52) CTSBALDH1A1KDM4ELMNASMN1; SMN2
SCHEMBL21044025 0.85 CTSB (0.52) CTSBALDH1A1KDM4ELMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111511728-B Compound for separating rare earth elements and s, p, d metals, separation method and use thereof 有机生物化学公司 2023-12-08 CN claimed
US-20230227942-A1 SEPARATION OF RARE EARTH ELEMENTS SHINE TECHNOLOGIES, LLC 2023-07-20 US claimed
CN-115836137-A Separation of rare earth elements 阳光科技公司 2023-03-21 CN claimed
EP-4127255-A1 SEPARATION OF RARE EARTH ELEMENTS SHINE Technologies, LLC (US) 2023-02-08 EP claimed
EP-3717466-B1 COMPOUNDS FOR SEPARATION OF RARE EARTH ELEMENTS AND S-, P-, D- METALS, METHOD OF SEPARATION, AND USE THEREOF USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR V V I (CZ) 2022-01-05 EP claimed
US-20200282331-A1 COMPOUNDS FOR SEPARATION OF RARE EARTH ELEMENTS AND S-, P-, D- METALS, METHOD OF SEPARATION, AND USE THEREOF USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I. (CZ) 2020-09-10 US claimed
EP-3492460-A1 COMPOUNDS FOR SEPARATION OF RARE EARTH ELEMENTS, METHOD OF SEPARATION, AND USE THEREOF Ustav Organicke Chemie A Biochemie Av Cr, V.v.i. (CZ) 2019-06-05 EP claimed
EP-0353450-B1 Macrocyclic bifunctional chelants, complexes thereof and their antibody conjugates DOW CHEMICAL CO (US) 1995-03-29 EP claimed
US-20250229198-A1 COMPOUNDS FOR SEPARATION OF RARE EARTH ELEMENTS AND S-, P-, D- METALS, METHOD OF SEPARATION, AND USE THEREOF USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I (CZ) 2025-07-17 US disclosed
US-12268977-B2 Compounds for separation of rare earth elements and s-, p-, d-metals, method of separation, and use thereof USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR. V.V.I. (CZ) 2025-04-08 US disclosed
CN-111511728-B Compound for separating rare earth elements and s, p, d metals, separation method and use thereof 有机生物化学公司 2023-12-08 CN disclosed
US-20230227942-A1 SEPARATION OF RARE EARTH ELEMENTS SHINE TECHNOLOGIES, LLC 2023-07-20 US disclosed
CN-115836137-A Separation of rare earth elements 阳光科技公司 2023-03-21 CN disclosed
EP-4127255-A1 SEPARATION OF RARE EARTH ELEMENTS SHINE Technologies, LLC (US) 2023-02-08 EP disclosed
US-5652361-A ANTITUMOR THE DOW CHEMICAL COMPANY (US) 1997-07-29 US disclosed
US-5435990-A Chelate-antibody complexes, treatment and diagnosis of cancer, tetraazacyclododecane compounds THE DOW CHEMICAL COMPANY (US) 1995-07-25 US disclosed
EP-0353450-B1 Macrocyclic bifunctional chelants, complexes thereof and their antibody conjugates DOW CHEMICAL CO (US) 1995-03-29 EP disclosed
EP-0420942-A1 MACROCYCLIC BIFUNCTIONAL CHELANTS, COMPLEXES THEREOF AND THEIR ANTIBODY CONJUGATES THE DOW CHEMICAL COMPANY (US) 1991-04-10 EP disclosed
EP-0353450-A1 Macrocyclic bifunctional chelants, complexes thereof and their antibody conjugates THE DOW CHEMICAL COMPANY (US) 1990-02-07 EP disclosed
WO-1989012631-A1 MACROCYCLIC BIFUNCTIONAL CHELANTS, COMPLEXES THEREOF AND THEIR ANTIBODY CONJUGATES THE DOW CHEMICAL COMPANY (US) 1989-12-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250229198-A1 COMPOUNDS FOR SEPARATION OF RARE EARTH ELEMENTS AND S-, P-, D- METALS, METHOD OF SEPARATION, AND USE THEREOF SCO2, SOD3, SLC39A3 CTSB 3740/4885ALDH1A1 4085/4885KDM4E 4827/4885
US-20200282331-A1 COMPOUNDS FOR SEPARATION OF RARE EARTH ELEMENTS AND S-, P-, D- METALS, METHOD OF SEPARATION, AND USE THEREOF SCLY, SFXN1, PTCD3 CTSB 3063/4885ALDH1A1 2634/4885KDM4E 4511/4885
US-12268977-B2 Compounds for separation of rare earth elements and s-, p-, d-metals, method of separation, and use thereof SCLY, SFXN1, PTCD3 CTSB 3063/4885ALDH1A1 2634/4885KDM4E 4511/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.