Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8882992 | 0.93 | SLC6A4 (0.33) | SLC6A4ALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL8710075 | 0.76 | NPC1 (0.44) | SLC6A4ALDH1A1MAPTHPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL8710124 | 0.75 | NPC1 (0.44) | SLC6A4ALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL29590612 | 0.73 | PTGS2 (0.37) | ALDH1A1HPGDHSD17B10KDM4EKMT2A | |
| SCHEMBL5678165 | 0.73 | PTGS2 (0.37) | ALDH1A1HPGDHSD17B10KDM4EKMT2A | |
| SCHEMBL547802 | 0.73 | PTGS2 (0.37) | ALDH1A1HPGDHSD17B10KDM4EKMT2A | |
| SCHEMBL29759482 | 0.73 | PTGS2 (0.37) | ALDH1A1HPGDHSD17B10KDM4EKMT2A | |
| SCHEMBL2026167 | 0.73 | PTGS2 (0.37) | ALDH1A1HPGDHSD17B10KDM4EKMT2A | |
| SCHEMBL5682194 | 0.67 | ALDH1A1 (0.39) | ALDH1A1MAPTHPGDHSD17B10KDM4E | |
| SCHEMBL5678330 | 0.67 | ALDH1A1 (0.39) | ALDH1A1MAPTHPGDHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5746840-A | Process for preparing enantiomerically pure 6-{4-chlorophenyl) (1 H-1,2,4-triazol-1-YL) methyl}-1-methyl-1 H-benzotriazole | JANSSEN PHARMACEUTICA, N.V. (BE) | 1998-05-05 | — | — | US | disclosed |
| US-5663354-A | Process for preparing enantiomerically pure 6-[(4-chlorophenyl) (1H-1,2,4-triazol-1-yl) methyl]-1-methyl-1H-benzotrizole | JANSSEN PHARMACEUTICA, N.V. (BE) | 1997-09-02 | — | — | US | disclosed |
| EP-0668861-A1 | PROCESS FOR PREPARING ENANTIOMERICALLY PURE 6- (4-CHLOROPHENYL)(1H --TRIAZOL-1,2,4-TRIAZOL-1-YL)METHYL]-1-METHYL-1H --BENZOTRIAZOLE | JANSSEN PHARMACEUTICA N.V. (BE) | 1995-08-30 | — | — | EP | disclosed |
| WO-1994011364-A1 | PROCESS FOR PREPARING ENANTIOMERICALLY PURE 6-[(4-CHLOROPHENYL)(1H^_-TRIAZOL-1,2,4-TRIAZOL-1-YL)METHYL]-1-METHYL-1H^_-BENZOTRIAZOLE | JANSSEN PHARMACEUTICA N.V. (BE) | 1994-05-26 | — | — | WO | disclosed |