Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | ACP3 | P15309 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8718439 | 0.89 | CYP2C19 (0.38) | KIF11ADRB2ADRB1NR3C2TAAR1 | |
| SCHEMBL8718508 | 0.88 | PNMT (0.42) | GRIN2BPNMTSLC6A2SLC6A4GAA | |
| SCHEMBL8716595 | 0.86 | PPARG (0.38) | MEN1RAB9AKMT2AKIF11ADRB2 | |
| SCHEMBL8716358 | 0.85 | GRIN2B (0.46) | KIF11NR3C2GRIN2BNR3C1PNMT | |
| SCHEMBL8715312 | 0.83 | MEN1 (0.41) | MEN1MAPTHTTKMT2ANR3C2 | |
| SCHEMBL8717503 | 0.81 | CBX7 (0.37) | KIF11ADRB2ADRB1NR3C2CYP3A4 | |
| SCHEMBL8714096 | 0.80 | ADRB2 (0.38) | ADRB2ADRB1NR3C2NR3C1TAAR1 | |
| SCHEMBL8715451 | 0.80 | TAAR1 (0.37) | KIF11ADRB2ADRB1NR3C2NR3C1 | |
| SCHEMBL8716625 | 0.78 | KIF11 (0.38) | KIF11ADRB2ADRB1NR3C2PNMT | |
| SCHEMBL8716822 | 0.77 | ADRB2 (0.39) | MEN1MAPTHTTKMT2AKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |