Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8714028 | 0.88 | TRPA1 (0.38) | TRPA1KDM4EL3MBTL1ALOX5OPRM1 | |
| SCHEMBL8714631 | 0.85 | CSNK1E (0.40) | TRPA1KDM4EL3MBTL1OPRM1OPRD1 | |
| SCHEMBL8719058 | 0.84 | IDH1 (0.36) | TRPA1KDM4EL3MBTL1ALOX5OPRM1 | |
| SCHEMBL8713556 | 0.84 | TRPA1 (0.41) | TRPA1KDM4EL3MBTL1OPRM1OPRD1 | |
| SCHEMBL8718544 | 0.81 | TRPA1 (0.46) | TRPA1KDM4EL3MBTL1OPRK1SIGMAR1 | |
| SCHEMBL8714031 | 0.80 | KDM4E (0.37) | TRPA1KDM4EL3MBTL1OPRM1OPRD1 | |
| SCHEMBL8430263 | 0.80 | SIGMAR1 (0.50) | TRPA1KDM4EL3MBTL1OPRK1SIGMAR1 | |
| SCHEMBL8716261 | 0.77 | TRPA1 (0.47) | TRPA1KDM4EL3MBTL1OPRK1SIGMAR1 | |
| SCHEMBL8089461 | 0.73 | KDM4E (0.46) | TRPA1KDM4EL3MBTL1OPRM1TSHR | |
| SCHEMBL5754344 | 0.73 | TAAR1 (0.47) | TRPA1KDM4EL3MBTL1OPRM1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |