Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP7 | P09237 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8715544 | 0.80 | TRPA1 (0.41) | KDM4EL3MBTL1OPRM1OPRD1OPRK1 | |
| SCHEMBL8713556 | 0.78 | TRPA1 (0.41) | KDM4EL3MBTL1OPRM1OPRD1OPRK1 | |
| SCHEMBL8714028 | 0.78 | TRPA1 (0.38) | KDM4EL3MBTL1OPRM1OPRD1OPRK1 | |
| SCHEMBL8714631 | 0.75 | CSNK1E (0.40) | KDM4EL3MBTL1OPRM1OPRD1OPRK1 | |
| SCHEMBL8430263 | 0.73 | SIGMAR1 (0.50) | KDM4EL3MBTL1OPRK1TRPA1SIGMAR1 | |
| SCHEMBL4540189 | 0.73 | OPRK1 (0.46) | SMN1; SMN2OPRM1OPRD1OPRK1SIGMAR1 | |
| SCHEMBL8716261 | 0.71 | TRPA1 (0.47) | KDM4EL3MBTL1OPRK1TRPA1SIGMAR1 | |
| Dimethylamine SCHEMBL28649942 | 0.69 | OPRK1 (0.45) | SMN1; SMN2OPRM1OPRD1OPRK1SIGMAR1 | |
| SCHEMBL8718544 | 0.69 | TRPA1 (0.46) | KDM4EL3MBTL1OPRK1TRPA1SIGMAR1 | |
| SCHEMBL10398265 | 0.68 | CYP2C19 (0.40) | KDM4EL3MBTL1SMN1; SMN2CYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |