SCHEMBL8718544

SCHEMBL8718544

CCC(C)C(Cc1ccccc1)N(CCO)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.46
ACE P12821 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
KDM4E B2RXH2 1/20 0.40
SIGMAR1 Q99720 6/20 0.39
CYP2D6 P10635 1/20 0.39
MME P08473 1/20 0.38
CPA1 P15085 1/20 0.38
ACE2 Q9BYF1 1/20 0.38
CYP3A4 P08684 1/20 0.37
TSHR P16473 1/20 0.37
SLC6A2 P23975 3/20 0.37
TAAR1 Q96RJ0 2/20 0.37
SLC6A4 P31645 2/20 0.37
SLC6A3 Q01959 2/20 0.37
MAOA P21397 1/20 0.37
CYP2A6 P11509 1/20 0.37
ADORA2A P29274 1/20 0.37
ADORA1 P30542 1/20 0.37
ADRA2B P18089 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8716261 0.88 TRPA1 (0.47) TRPA1L3MBTL1KDM4ESIGMAR1CYP2D6
SCHEMBL8715544 0.81 TRPA1 (0.41) TRPA1L3MBTL1KDM4ESIGMAR1CYP3A4
SCHEMBL8430263 0.81 SIGMAR1 (0.50) TRPA1L3MBTL1KDM4ESIGMAR1CYP2D6
SCHEMBL8713556 0.76 TRPA1 (0.41) TRPA1L3MBTL1KDM4ESIGMAR1CYP2D6
SCHEMBL8714028 0.76 TRPA1 (0.38) TRPA1L3MBTL1KDM4ESIGMAR1TSHR
SCHEMBL8089461 0.75 KDM4E (0.46) TRPA1L3MBTL1KDM4ECYP3A4TSHR
SCHEMBL5754344 0.75 TAAR1 (0.47) TRPA1L3MBTL1KDM4ECYP3A4TAAR1
SCHEMBL8714631 0.74 CSNK1E (0.40) TRPA1L3MBTL1KDM4ESIGMAR1SLC6A2
SCHEMBL30885596 0.73 KDM4E (0.49) TRPA1L3MBTL1KDM4ECYP3A4SLC6A2
SCHEMBL2772902 0.72 KDM4E (0.44) TRPA1L3MBTL1KDM4ESIGMAR1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5811293-A CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1998-09-22 US disclosed