Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8714631 | 0.91 | CSNK1E (0.40) | TRPA1L3MBTL1KDM4ESIGMAR1OPRM1 | |
| SCHEMBL8715544 | 0.88 | TRPA1 (0.41) | TRPA1L3MBTL1KDM4ESIGMAR1OPRM1 | |
| SCHEMBL8713556 | 0.82 | TRPA1 (0.41) | TRPA1L3MBTL1KDM4ESIGMAR1OPRM1 | |
| SCHEMBL8714031 | 0.78 | KDM4E (0.37) | TRPA1L3MBTL1KDM4ESIGMAR1OPRM1 | |
| SCHEMBL8430263 | 0.78 | SIGMAR1 (0.50) | TRPA1L3MBTL1KDM4ESIGMAR1OPRK1 | |
| SCHEMBL11117786 | 0.77 | OPRK1 (0.48) | SIGMAR1OPRD1OPRK1TSHR | |
| SCHEMBL4617535 | 0.76 | NPC1 (0.38) | L3MBTL1KDM4ESIGMAR1CSNK1E | |
| SCHEMBL8718544 | 0.76 | TRPA1 (0.46) | TRPA1L3MBTL1KDM4ESIGMAR1OPRK1 | |
| Iodide SCHEMBL5092821 | 0.75 | OPRK1 (0.47) | SIGMAR1OPRD1OPRK1TSHR | |
| Bromide SCHEMBL5092308 | 0.75 | OPRK1 (0.47) | SIGMAR1OPRD1OPRK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |