Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 17/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8409543 | 0.79 | KDM1A (0.41) | KDM1ALRRK2 | |
| SCHEMBL8407178 | 0.76 | KDM1A (0.38) | KDM1ALRRK2 | |
| SCHEMBL8409542 | 0.75 | MAOB (0.52) | LTA4H | |
| SCHEMBL8409450 | 0.74 | KDM1A (0.40) | KDM1A | |
| SCHEMBL8715690 | 0.74 | LTA4H (0.48) | KDM1ALTA4H | |
| SCHEMBL8407175 | 0.74 | GAA (0.47) | KDM1A | |
| SCHEMBL8407652 | 0.72 | HRH2 (0.45) | KDM1AFFAR4 | |
| SCHEMBL8720191 | 0.71 | GRM3 (0.54) | KDM1A | |
| SCHEMBL8409445 | 0.71 | CHRM4 (0.52) | KDM1ALTA4H | |
| SCHEMBL8720195 | 0.71 | KDM1A (0.36) | KDM1ALRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5736559-A | CARDIOVASCULAR DISORDERS; RESPIRATORY SYSTEM DISORDERS | KARL THOMAE GMBH (DE) | 1998-04-07 | — | — | US | disclosed |