Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 13/20 | 0.36 |
| ▸ | USP14 | P54578 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8717927 | 0.95 | USP30 (0.36) | KDM1AUSP30 | |
| SCHEMBL8410942 | 0.91 | USP14 (0.43) | KDM1AUSP14USP30CHRM3 | |
| SCHEMBL8407571 | 0.89 | SIGMAR1 (0.37) | KDM1AUSP14USP30 | |
| SCHEMBL8719954 | 0.80 | USP14 (0.42) | KDM1AUSP14 | |
| SCHEMBL8409444 | 0.79 | POLB (0.38) | — | |
| Hydrochloric Acid SCHEMBL8714669 | 0.75 | LTA4H (0.33) | — | |
| SCHEMBL8409543 | 0.74 | KDM1A (0.41) | KDM1AUSP14CHRM3LRRK2 | |
| SCHEMBL8407178 | 0.73 | KDM1A (0.38) | KDM1AUSP14CHRM3LRRK2 | |
| SCHEMBL8409542 | 0.72 | MAOB (0.52) | — | |
| SCHEMBL8720191 | 0.72 | GRM3 (0.54) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5736559-A | CARDIOVASCULAR DISORDERS; RESPIRATORY SYSTEM DISORDERS | KARL THOMAE GMBH (DE) | 1998-04-07 | — | — | US | disclosed |