Dibrompropamidine

Dibrompropamidine

SCHEMBL871570

N=C(N)c1ccc(OCCCOc2ccc(C(=N)N)cc2Br)c(Br)c1.O=S(=O)(O)CCO

nearest known ligand 0.72

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F2 P00734 2/20 0.72
PLAU P00749 1/20 0.72
ST14 Q9Y5Y6 1/20 0.72
POLB P06746 3/20 0.60
ALDH1A1 P00352 2/20 0.60
LMNA P02545 2/20 0.60
RAB9A P51151 2/20 0.60
SMN1; SMN2 Q16637 2/20 0.60
MAPT P10636 2/20 0.60
KDM4E B2RXH2 2/20 0.60
NPC1 O15118 1/20 0.60
ALOX15 P16050 1/20 0.60
BRCA1 P38398 1/20 0.60
HTT P42858 1/20 0.60
GMNN O75496 1/20 0.60
PKM P14618 1/20 0.60
THPO P40225 1/20 0.60
MTOR P42345 1/20 0.60
RECQL P46063 1/20 0.60
BLM P54132 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dibrompropamidine SCHEMBL2471251 1.00 F2 (0.72) F2PLAUST14POLBALDH1A1
Dibrompropamidine SCHEMBL30231952 1.00 F2 (0.72) F2PLAUST14POLBALDH1A1
SCHEMBL20528835 0.96 F2 (0.67) F2PLAUST14POLBALDH1A1
SCHEMBL3006160 0.96 F2 (0.67) F2PLAUST14POLBALDH1A1
SCHEMBL985038 0.96 F2 (0.67) F2PLAUST14POLBALDH1A1
Dibrompropamidine SCHEMBL29709297 0.85 F2 (1.00) F2PLAUST14PRSS1
Dibrompropamidine SCHEMBL292947 0.85 F2 (1.00) F2PLAUST14PRSS1
Dibrompropamidine SCHEMBL29232796 0.84 F2 (0.71) F2PLAUST14PRSS1
Dibrompropamidine SCHEMBL21083095 0.84 F2 (0.97) F2PLAUST14PRSS1
SCHEMBL14599538 0.81 F2 (0.90) F2PLAUST14PRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 175 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250346910-A1 METHODS AND COMPOSITIONS TO PREVENT MICROBIAL INFECTION COMMENSE BIO INC (US) 2025-11-13 US claimed
US-20230363380-A1 INSTRINSICALLY ANTIMICROBIAL POROSIC MATRIX COMPOSITES AND METHOD OF MANUFACTURE THEREOF WILSON JOHN PAUL (US) 2023-11-16 US claimed
US-20220288135-A1 LIVE BIOTHERAPEUTIC COMPOSITIONS AND METHODS BioPlx, Inc. (US) 2022-09-15 US claimed
EP-3996510-A2 LIVE BIOTHERAPEUTIC COMPOSITIONS AND METHODS BioPlx, Inc. (US) 2022-05-18 EP claimed
US-20220079145-A1 INSTRINSICALLY ANTIMICROBIAL POROSIC MATRIX COMPOSITES AND METHOD OF MANUFACTURE THEREOF WILSON JOHN PAUL (US) 2022-03-17 US claimed
WO-2021007341-A2 LIVE BIOTHERAPEUTIC COMPOSITIONS AND METHODS BioPlx, Inc. (US) 2021-01-14 WO claimed
US-10806741-B2 Treatments for free-living amoebic infections PROFOUNDA, INC. (US) 2020-10-20 US claimed
EP-3720458-A1 METHODS AND COMPOSITIONS TO PREVENT MICROBIAL INFECTION BioPlx, Inc. (US) 2020-10-14 EP claimed
WO-2020068562-A1 NOVEL TREATMENTS FOR FREE-LIVING AMOEBIC INFECTIONS PROFOUNDA, INC. (US) 2020-04-02 WO claimed
US-20200093842-A1 NOVEL TREATMENTS FOR FREE-LIVING AMOEBIC INFECTIONS PROFOUNDA, INC. (US) 2020-03-26 US claimed
US-20190169623-A1 METHODS AND COMPOSITIONS TO PREVENT MICROBIAL INFECTION COMMENSE BIO, INC. 2019-06-06 US claimed
EP-2376074-B1 METHOD FOR IMPROVED BIOACTIVATION OF MEDICATIONS DRITTE PATENTPORTFOLIO BETEILI (DE) 2019-03-13 EP claimed
US-20070128121-A1 Polymer hydrogels for controlled release and absorption of biocides THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2007-06-07 US claimed
EP-0423391-B1 Toilet bowl cleaners containing iodophors KIWI BRANDS INC (US) 1994-08-24 EP claimed
EP-0580627-A1 PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF GASTRITIS SMITHKLINE BEECHAM PLC (GB) 1994-02-02 EP claimed
WO-1992018111-A2 PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF GASTRITIS SMITHKLINE BEECHAM PLC (GB) 1992-10-29 WO claimed
EP-0423391-A1 Toilet bowl cleaners containing iodophors KIWI BRANDS INC (US) 1991-04-24 EP claimed
US-4911859-A Polyoxyethylene oxide KIWI BRANDS, INC. (US) 1990-03-27 US claimed
WO-1984004456-A1 IMPROVED COMPOSITIONS FOR TREATING INFECTED BURN WOUNDS UNIV STRATHCLYDE (GB) 1984-11-22 WO claimed
EP-0125858-A1 Improved compositions for treating infected burn wounds University of Strathclyde (GB) 1984-11-21 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10806741-B2 Treatments for free-living amoebic infections TUBB4B, TUBB2B, TUBB F2 1787/4885PLAU 1823/4885ST14 2362/4885
US-20070128121-A1 Polymer hydrogels for controlled release and absorption of biocides USP21, PHB2, BAP1 F2 4558/4885PLAU 1487/4885ST14 256/4885
US-20200093842-A1 NOVEL TREATMENTS FOR FREE-LIVING AMOEBIC INFECTIONS TUBB4B, CHMP4B, TUBB2B F2 2724/4885PLAU 1843/4885ST14 2855/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.