Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 3/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TACR3 | P29371 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8715705 | 0.75 | TACR1 (0.46) | CTSLCTSSCTSKTACR1TACR3 | |
| SCHEMBL9338291 | 0.75 | CCKBR (0.44) | CCKBRTACR1KDM4EAPAF1POLB | |
| SCHEMBL8705350 | 0.73 | PKM (0.47) | TACR1KDM4EAPAF1POLBMAPT | |
| SCHEMBL19100705 | 0.68 | CTSL (0.58) | CTSLCTSSCTSKFAAHTACR1 | |
| SCHEMBL8892465 | 0.67 | KDM4E (0.49) | CCKBRTACR1KDM4EAPAF1POLB | |
| SCHEMBL8892454 | 0.67 | KDM4E (0.49) | CCKBRTACR1KDM4EAPAF1POLB | |
| SCHEMBL5745010 | 0.66 | MEN1 (0.67) | FAAHPOLBMEN1LMNACYP1A2 | |
| SCHEMBL8829818 | 0.66 | GPR84 (0.48) | KDM4EAPAF1POLBMAPTRECQL | |
| SCHEMBL8829820 | 0.66 | GPR84 (0.48) | KDM4EAPAF1POLBMAPTRECQL | |
| SCHEMBL200589 | 0.66 | MAPT (0.54) | KDM4EAPAF1POLBMAPTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726200-A | Pro-drugs for CCK antagonists | WARNER-LAMBERT COMPANY (US) | 1998-03-10 | — | — | US | disclosed |