Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | EDNRA | P25101 | 1/20 | 0.42 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8877169 | 0.90 | LTA4H (0.46) | SRD5A2MRGPRX4LTA4HPLA2G2ATRPM8 | |
| SCHEMBL7373630 | 0.85 | KDM4E (0.53) | TDP1L3MBTL1 | |
| SCHEMBL7374645 | 0.82 | PRKAG1 (0.46) | MAPTTDP1HTT | |
| SCHEMBL29617921 | 0.79 | LTA4H (0.48) | SRD5A2LTA4HPLA2G2ATRPM8ADORA3 | |
| SCHEMBL2858690 | 0.79 | CDK9 (0.54) | MAPTL3MBTL1HTT | |
| SCHEMBL2857475 | 0.75 | TRPA1 (0.49) | MAPTL3MBTL1HTT | |
| SCHEMBL16714058 | 0.75 | LTA4H (0.60) | SRD5A2MRGPRX4LTA4HPLA2G2ATRPM8 | |
| SCHEMBL2426791 | 0.72 | LTA4H (0.58) | LTA4HSGMS2 | |
| SCHEMBL30848623 | 0.72 | LTA4H (0.58) | LTA4HSGMS2 | |
| SCHEMBL492695 | 0.72 | HAO1 (0.60) | SRD5A2LTA4HPLA2G2AHAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708105-B1 | 5-HT4 receptor agonists | NISSHIN FLOUR MILLING CO (JP) | 1998-12-23 | — | — | EP | disclosed |
| US-5684003-A | GASTROINTESTINAL DISORDERS OR ANTIULCER AGENTS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-11-04 | — | — | US | disclosed |
| EP-0708105-A1 | 5-HT4 receptor agonists | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1996-04-24 | — | — | EP | disclosed |