Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.51 |
| ▸ | NOD2 | Q9HC29 | 4/20 | 0.45 |
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.44 |
| ▸ | BCL2 | P10415 | 1/20 | 0.44 |
| ▸ | BID | P55957 | 1/20 | 0.44 |
| ▸ | CCR2 | P41597 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8716050 | 0.84 | NOD2 (0.49) | ALDH1A1LMNAMAPTHDAC3HDAC4 | |
| SCHEMBL7066595 | 0.80 | ALDH1A1 (0.49) | ALDH1A1LMNAMAPTHDAC3HDAC4 | |
| SCHEMBL7066115 | 0.79 | BCL2 (0.56) | ALDH1A1LMNAMAPTHDAC3HDAC4 | |
| SCHEMBL7067783 | 0.78 | HDAC3 (0.57) | ALDH1A1LMNAMAPTHDAC3HDAC4 | |
| SCHEMBL7859137 | 0.78 | PLK1 (0.49) | LMNAHDAC1HDAC2HDAC6DRD2 | |
| SCHEMBL7061634 | 0.78 | CCR2 (0.55) | ALDH1A1LMNAMAPTHDAC3HDAC4 | |
| SCHEMBL7066194 | 0.77 | HDAC3 (0.53) | ALDH1A1LMNAMAPTHDAC3HDAC4 | |
| SCHEMBL7065121 | 0.77 | HDAC1 (0.52) | ALDH1A1LMNAMAPTHDAC3HDAC4 | |
| SCHEMBL7063702 | 0.76 | HDAC3 (0.55) | ALDH1A1LMNAMAPTHDAC3HDAC4 | |
| SCHEMBL6172779 | 0.76 | HDAC3 (0.65) | ALDH1A1LMNAMAPTHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760040-A | THERAPEUTIC AGENT FOR PROSTATIC HYPERTROPHY, URINATION DISORDER, ALOPECIA AND ACNE | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-02 | — | — | US | disclosed |