Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 2/20 | 0.41 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 12/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6326896 | 0.88 | GHSR (0.42) | GHSRBDKRB2TACR1 | |
| SCHEMBL3394198 | 0.82 | TACR1 (0.38) | GHSRTACR1 | |
| SCHEMBL6316765 | 0.82 | BDKRB2 (0.45) | GHSRBDKRB2TACR1MMP9MMP8 | |
| SCHEMBL6319068 | 0.81 | GHSR (0.49) | GHSRBDKRB2TACR1 | |
| SCHEMBL6319064 | 0.81 | GHSR (0.49) | GHSRBDKRB2TACR1 | |
| SCHEMBL6318539 | 0.74 | GHSR (0.58) | GHSRBDKRB2TACR1 | |
| SCHEMBL6318536 | 0.74 | GHSR (0.58) | GHSRBDKRB2TACR1 | |
| SCHEMBL14527562 | 0.72 | MMP9 (0.46) | BDKRB2TACR1MMP9MMP8 | |
| SCHEMBL3266625 | 0.71 | GHSR (0.50) | GHSRTACR1 | |
| SCHEMBL3266633 | 0.71 | GHSR (0.50) | GHSRTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869974-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997023508-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1997-07-03 | — | — | WO | disclosed |