SCHEMBL6326896

SCHEMBL6326896

CN[C@H](Cc1ccc2ccccc2c1)C(=O)N(C)[C@H](Cc1ccccc1)C(=O)NC1CC1.NC1(CC=CC(=O)O)CCC1

nearest known ligand 0.47

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GHSR Q92847 2/20 0.42
BDKRB2 P30411 1/20 0.38
TACR1 P25103 9/20 0.37
F2 P00734 2/20 0.37
FCER2 P06734 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6319068 0.89 GHSR (0.49) GHSRBDKRB2TACR1
SCHEMBL6319064 0.89 GHSR (0.49) GHSRBDKRB2TACR1
SCHEMBL8715798 0.88 GHSR (0.41) GHSRBDKRB2TACR1
SCHEMBL6316765 0.87 BDKRB2 (0.45) GHSRBDKRB2TACR1F2FCER2
SCHEMBL3267249 0.78 GHSR (0.50) GHSRTACR1
SCHEMBL3267246 0.78 GHSR (0.50) GHSRTACR1
SCHEMBL4427112 0.77 FCER2 (0.53) GHSRTACR1F2FCER2
SCHEMBL4426088 0.77 FCER2 (0.53) GHSRTACR1F2FCER2
SCHEMBL6317992 0.77 FCER2 (0.53) GHSRTACR1F2FCER2
SCHEMBL6319205 0.76 NPY5R (0.49) GHSRTACR1FCER2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6939880-B2 Compounds with growth hormone releasing properties NOVO NORDISK A/S (DK) 2005-09-06 US disclosed
US-20030055261-A1 Compounds with growth hormone releasing properties HELSINN THERAPEUTICS (U.S.), INC. 2003-03-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030055261-A1 Compounds with growth hormone releasing properties GHRHR, GHSR, IGFBP1 GHSR 2/4885BDKRB2 212/4885TACR1 241/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.