Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL8716042

N[C@H]1CCC[C@H](N)C1.O=C(O)C(F)(F)F

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CHRM3 P20309 1/20 0.36
OAT P04181 1/20 0.35
SLC1A2 P43004 2/20 0.33
GABRR1 P24046 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL7211625 1.00 CHRM3 (0.36) CHRM3OATSLC1A2GABRR1
Trifluoroacetic Acid SCHEMBL31447631 1.00 CHRM3 (0.36) CHRM3OATSLC1A2GABRR1
Trifluoroacetic Acid SCHEMBL7212392 1.00 CHRM3 (0.36) CHRM3OATSLC1A2GABRR1
Trifluoroacetic Acid SCHEMBL3708706 0.88 OAT (0.34) CHRM3OATGABRR1
Trifluoroacetic Acid SCHEMBL14859202 0.86 OAT (0.41) CHRM3OATSLC1A2GABRR1
Trifluoroacetic Acid SCHEMBL14858314 0.86 OAT (0.41) CHRM3OATSLC1A2GABRR1
Trifluoroacetic Acid SCHEMBL3043598 0.86 MMP8 (0.33) CHRM3OATSLC1A2
Cycloheptanamine SCHEMBL27746259 0.84 ALDH1A1 (0.36) CHRM3
Cyclohexylamine SCHEMBL1787821 0.84 ALDH1A1 (0.36) CHRM3
Bicarbonate SCHEMBL8358952 0.83 GABRR1 (0.39) OATGABRR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5736557-A MICROBIOCIDE EFFECTIVE AGAINST CHLOROQUINE-RESISTANT AND CHLOROQUINE-SENSITIVE STRAINS OF PLASMODIUM FALCIPARUM HOFFMAN-LA ROCHE, INC. (US) 1998-04-07 US disclosed