Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | CFD | P00746 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CASR | P41180 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8714126 | 0.91 | KIF11 (0.33) | SLC6A2SLC6A4SLC6A3NR3C1CFD | |
| SCHEMBL8716208 | 0.90 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3NR3C1NR3C2 | |
| SCHEMBL8713610 | 0.88 | LMNA (0.43) | NR3C1NR3C2CASR | |
| SCHEMBL8713910 | 0.88 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3NR3C1NR3C2 | |
| SCHEMBL8718570 | 0.84 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3NR3C1NR3C2 | |
| SCHEMBL8714242 | 0.84 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3NR3C1NR3C2 | |
| SCHEMBL8713790 | 0.81 | NR3C1 (0.47) | SLC6A2SLC6A4SLC6A3NR3C1NR3C2 | |
| SCHEMBL8713660 | 0.80 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3HTTPNMT | |
| SCHEMBL8716358 | 0.78 | GRIN2B (0.46) | SLC6A2SLC6A4SLC6A3NR3C1NR3C2 | |
| SCHEMBL8713286 | 0.78 | TP53 (0.44) | HTTPNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |