Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 5/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | CASR | P41180 | 4/20 | 0.37 |
| ▸ | GNRHR | P30968 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8719259 | 0.90 | NR3C1 (0.39) | LMNANR3C1NR3C2PGRCASR | |
| SCHEMBL8716161 | 0.88 | SLC6A2 (0.36) | NR3C1NR3C2CASR | |
| SCHEMBL8720320 | 0.86 | NR3C1 (0.41) | LMNANR3C1NR3C2GNRHRL3MBTL1 | |
| SCHEMBL8714126 | 0.85 | KIF11 (0.33) | NR3C1GNRHRADRB2 | |
| SCHEMBL8713790 | 0.85 | NR3C1 (0.47) | NR3C1NR3C2PGRCASRIDO1 | |
| SCHEMBL8716180 | 0.84 | IDO1 (0.41) | LMNANR3C1NR3C2L3MBTL1ALDH1A1 | |
| SCHEMBL8713152 | 0.83 | RAB9A (0.39) | LMNANR3C1NR3C2PGRCASR | |
| SCHEMBL8716634 | 0.81 | NR3C1 (0.38) | LMNANR3C1NR3C2L3MBTL1ALDH1A1 | |
| SCHEMBL8716700 | 0.81 | MPO (0.40) | LMNANR3C1NR3C2ALDH1A1IDO1 | |
| SCHEMBL8716208 | 0.78 | SLC6A2 (0.38) | NR3C1NR3C2GNRHRADRB2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |