Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.56 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.55 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.55 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3996389 | 0.84 | IL4I1 (0.47) | RAB9AMRGPRX4ALDH1A1NPC1LMNA | |
| SCHEMBL2069334 | 0.81 | LOXL2 (0.68) | LOXL2CYP4F2CYP4A11SLC7A5HIF1A | |
| SCHEMBL6757752 | 0.78 | HIF1A (0.57) | LOXL2CYP4F2CYP4A11SLC7A5HIF1A | |
| SCHEMBL8716270 | 0.78 | LOXL2 (0.60) | LOXL2CYP4F2CYP4A11SLC7A5HIF1A | |
| SCHEMBL70173 | 0.75 | CYP4F2 (0.83) | LOXL2CYP4F2CYP4A11SLC7A5HIF1A | |
| SCHEMBL126284 | 0.75 | LOXL2 (0.74) | LOXL2CYP4F2CYP4A11SLC7A5HIF1A | |
| SCHEMBL481481 | 0.75 | CYP4F2 (0.67) | LOXL2CYP4F2CYP4A11SLC7A5HIF1A | |
| SCHEMBL12797648 | 0.75 | LOXL2 (0.64) | LOXL2CYP4F2CYP4A11SLC7A5HIF1A | |
| SCHEMBL6978758 | 0.75 | CHRM2 (0.49) | KMT2A | |
| SCHEMBL45633 | 0.74 | LOXL2 (0.68) | LOXL2CYP4F2CYP4A11SLC7A5HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763469-A | Substituted cyclic ureas and derivatives thereof useful as retroviral protease inhibitors | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-06-09 | — | — | US | disclosed |