Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8716507 | 1.00 | ADRB2 (0.47) | ADRB2ADRB1ADRB3ALDH1A1RECQL | |
| SCHEMBL8716638 | 0.87 | ADRB2 (0.62) | ADRB2ADRB1ADRB3HIF1ACYP2D6 | |
| SCHEMBL8716636 | 0.87 | ADRB2 (0.62) | ADRB2ADRB1ADRB3HIF1ACYP2D6 | |
| SCHEMBL8718471 | 0.86 | LTA4H (0.54) | PPARGPPARAMEN1POLBMAPK1 | |
| SCHEMBL8718467 | 0.86 | LTA4H (0.54) | PPARGPPARAMEN1POLBMAPK1 | |
| SCHEMBL8716601 | 0.84 | SLC6A4 (0.53) | ALDH1A1PPARGPPARAADRA2AADRA2C | |
| SCHEMBL8716604 | 0.84 | SLC6A4 (0.53) | ALDH1A1PPARGPPARAADRA2AADRA2C | |
| SCHEMBL8716539 | 0.84 | NPY5R (0.41) | ALDH1A1ADRA2AADRA2CLMNAHIF1A | |
| SCHEMBL8716542 | 0.84 | NPY5R (0.41) | ALDH1A1ADRA2AADRA2CLMNAHIF1A | |
| SCHEMBL8713316 | 0.82 | ALDH1A1 (0.52) | ADRB1ADRB3ALDH1A1ADRA2AADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |