Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LTA4H | P09960 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.38 |
| ▸ | LAP3 | P28838 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8716542 | 1.00 | NPY5R (0.41) | NPY5RESR1ESR2KDM4EADRA2A | |
| SCHEMBL8713418 | 0.86 | ADRB2 (0.47) | HIF1AMAOBAOC3CYP2D6 | |
| SCHEMBL8713420 | 0.86 | ADRB2 (0.47) | HIF1AMAOBAOC3CYP2D6 | |
| SCHEMBL8718467 | 0.85 | LTA4H (0.54) | NPY5RMAOBMEN1POLBMAPK1 | |
| SCHEMBL8718471 | 0.85 | LTA4H (0.54) | NPY5RMAOBMEN1POLBMAPK1 | |
| SCHEMBL8716504 | 0.84 | ADRB2 (0.47) | NPY5RKDM4EADRA2AADRA2CLMNA | |
| SCHEMBL8716507 | 0.84 | ADRB2 (0.47) | NPY5RKDM4EADRA2AADRA2CLMNA | |
| SCHEMBL8716604 | 0.83 | SLC6A4 (0.53) | KDM4EADRA2AADRA2CLMNAHIF1A | |
| SCHEMBL8716601 | 0.83 | SLC6A4 (0.53) | KDM4EADRA2AADRA2CLMNAHIF1A | |
| SCHEMBL8714019 | 0.81 | CYP2D6 (0.58) | KDM4EADRA2AADRA2CLMNAHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |