Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8718439 | 0.89 | CYP2C19 (0.38) | LMNACYP2C19KIF11ADRB2ADRB1 | |
| SCHEMBL8716588 | 0.88 | SLC6A2 (0.39) | PPARGPPARAGRIN2DGRIN3BGRIN1 | |
| SCHEMBL8713638 | 0.86 | MEN1 (0.35) | RAB9AGRIN2BCYP3A4KDM4EMEN1 | |
| SCHEMBL8717503 | 0.86 | CBX7 (0.37) | CYP3A4CYP2D6KIF11ADRB2ADRB1 | |
| SCHEMBL8716625 | 0.86 | KIF11 (0.38) | KIF11ADRB2ADRB1NR3C2 | |
| SCHEMBL8717467 | 0.83 | MEN1 (0.48) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL8716735 | 0.81 | SLC6A2 (0.38) | GRIN2BLMNAKMT2AKIF11TAAR1 | |
| SCHEMBL8714096 | 0.80 | ADRB2 (0.38) | LMNAKDM4EADRB2ADRB1NR3C2 | |
| SCHEMBL8713660 | 0.79 | SLC6A2 (0.41) | LMNACYP2D6NFKB1CYP2C19KIF11 | |
| SCHEMBL8718508 | 0.78 | PNMT (0.42) | GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |