Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8430263 | 0.79 | SIGMAR1 (0.50) | SIGMAR1TRPA1ADRA2BADRA2CADRA1A | |
| SCHEMBL8714206 | 0.79 | SIGMAR1 (0.44) | SIGMAR1TRPA1ADRA2BADRA2CADRA1A | |
| SCHEMBL8713645 | 0.79 | SIGMAR1 (0.44) | SIGMAR1TRPA1ADRA2BADRA2CADRA1A | |
| SCHEMBL8718245 | 0.78 | PNMT (0.42) | SIGMAR1TRPA1ADRA2BADRA2CADRA1A | |
| SCHEMBL8717109 | 0.76 | SIGMAR1 (0.43) | SIGMAR1TRPA1ADRA2BADRA2CADRA1A | |
| SCHEMBL8713821 | 0.75 | ALDH1A1 (0.45) | ADRA1AMEN1MAPTKMT2ALMNA | |
| SCHEMBL8714022 | 0.75 | SIGMAR1 (0.43) | SIGMAR1TRPA1ADRA2BADRA2CADRA1A | |
| SCHEMBL8714026 | 0.74 | MAOB (0.49) | SIGMAR1MEN1KMT2AMAOBMAOA | |
| SCHEMBL8718156 | 0.74 | SIGMAR1 (0.42) | SIGMAR1TRPA1ADRA2BADRA2CADRA1A | |
| SCHEMBL8713177 | 0.73 | SIGMAR1 (0.40) | SIGMAR1TRPA1ADRA2BADRA2CADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |