Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PFKFB2 | O60825 | 1/20 | 0.41 |
| ▸ | PFKFB1 | P16118 | 1/20 | 0.41 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10119320 | 0.93 | ALDH1A1 (0.43) | ALDH1A1KDM4ELMNAPFKFB2PFKFB1 | |
| SCHEMBL845392 | 0.91 | ALDH1A1 (0.51) | ALDH1A1KDM4ELMNAHSD17B10USP2 | |
| SCHEMBL874311 | 0.87 | ALDH1A1 (0.47) | ALDH1A1KDM4ELMNAPFKFB2PFKFB1 | |
| SCHEMBL873465 | 0.86 | KDM4E (0.47) | ALDH1A1KDM4ELMNAPFKFB2PFKFB1 | |
| SCHEMBL874324 | 0.85 | MAPK1 (0.42) | ALDH1A1LMNACYP2C9CYP2C19TRPV1 | |
| SCHEMBL874056 | 0.85 | TRPV1 (0.42) | ALDH1A1TSHRCYP2C9CYP2C19MEN1 | |
| SCHEMBL872044 | 0.85 | ALDH1A1 (0.43) | ALDH1A1KDM4ELMNAPFKFB2PFKFB1 | |
| SCHEMBL845110 | 0.84 | ALDH1A1 (0.48) | ALDH1A1KDM4ELMNAPFKFB2PFKFB1 | |
| SCHEMBL873862 | 0.84 | ALDH1A1 (0.45) | ALDH1A1KDM4ELMNAPFKFB2PFKFB1 | |
| SCHEMBL10119315 | 0.84 | MAPT (0.40) | ALDH1A1PFKFB2PFKFB1PFKFB3CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143288-B2 | Inhibitors of HCV replication | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-03-27 | — | — | US | disclosed |