Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9273636 | 0.76 | ALDH1A1 (0.35) | PDPK1AXL | |
| SCHEMBL8717177 | 0.73 | LRRK2 (0.38) | PDPK1 | |
| SCHEMBL8720060 | 0.73 | GAA (0.40) | PDPK1AXL | |
| SCHEMBL20256207 | 0.68 | PDK1 (0.35) | — | |
| SCHEMBL18627081 | 0.57 | CYP1A2 (0.48) | — | |
| Phenothiazine SCHEMBL5338471 | 0.56 | NOX1 (0.59) | — | |
| SCHEMBL31666049 | 0.55 | TOP1 (0.32) | — | |
| SCHEMBL12075256 | 0.54 | TGFBR1 (0.51) | — | |
| SCHEMBL15074585 | 0.54 | HSP90AA1 (0.43) | — | |
| SCHEMBL2330553 | 0.54 | MAPT (0.48) | AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0837861-A1 | NEW PYRIDO-THIOPYRANOINDAZOLES WITH ANTITUMOR ACTIVITY | THE UNIVERSITY OF VERMONT (US) | 1998-04-29 | — | — | EP | disclosed |
| WO-1997002267-A1 | NEW PYRIDO-THIOPYRANOINDAZOLES WITH ANTITUMOR ACTIVITY | UNIVERSITY OF VERMONT (US) | 1997-01-23 | — | — | WO | disclosed |