Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8717763 | 0.86 | KDM4E (0.46) | KDM4EALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL8715083 | 0.83 | KDM4E (0.53) | KDM4EALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL8714799 | 0.81 | KDM4E (0.53) | KDM4EALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL8717501 | 0.76 | MPO (0.53) | KDM4EMEN1KMT2AHCRTR1MPO | |
| SCHEMBL10905707 | 0.68 | MTNR1A (0.65) | KDM4EALDH1A1MEN1KMT2AMPO | |
| SCHEMBL8711714 | 0.67 | MPO (0.51) | KDM4EMEN1KMT2AHCRTR1MPO | |
| SCHEMBL8711894 | 0.67 | MPO (0.53) | MPOHPGDMTNR1AMTNR1B | |
| SCHEMBL23417935 | 0.66 | ALDH1A1 (1.00) | KDM4EALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL8715597 | 0.65 | MTNR1A (0.67) | KDM4EALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL8712074 | 0.64 | MPO (0.47) | KDM4EMEN1KMT2AMPOHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5770610-A | ADMINISTERING R-(+)-N-(2-METHYL-2-(5-METHOXY-6-CHLOROINDOL-3-YL)ETHYL) ACETAMIDE | ELI LILLY AND COMPANY (US) | 1998-06-23 | — | — | US | disclosed |