Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.32 |
| ▸ | IDH1 | O75874 | 3/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8714349 | 0.82 | HSD11B1 (0.35) | HSD11B1IDH1ADRA2AADRA2BADRA2C | |
| SCHEMBL8719427 | 0.73 | UGT2B7 (0.38) | HSD11B1 | |
| SCHEMBL8717846 | 0.73 | ALOX5AP (0.37) | — | |
| SCHEMBL9246183 | 0.72 | CYP19A1 (0.38) | HSD11B1 | |
| SCHEMBL8714480 | 0.72 | SLC18A2 (0.35) | — | |
| SCHEMBL9244481 | 0.72 | REN (0.37) | HSD11B1ADRA2AADRA2BADRA2C | |
| SCHEMBL9250623 | 0.65 | SLC6A3 (0.40) | HSD11B1 | |
| SCHEMBL9249054 | 0.64 | POLB (0.35) | — | |
| SCHEMBL8715153 | 0.64 | SLC6A2 (0.43) | HSD11B1IDH1ADRA2AADRA2BADRA2C | |
| SCHEMBL8714354 | 0.60 | HRH3 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719291-A | FUNGICIDE | HOFFMANN-LA ROCHE INC. (US) | 1998-02-17 | — | — | US | disclosed |