Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 11/20 | 0.78 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.78 |
| ▸ | MPO | P05164 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | HTR1A | P08908 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | NQO2 | P16083 | 1/20 | 0.63 |
| ▸ | HTR2B | P41595 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | BLM | P54132 | 1/20 | 0.63 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.63 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.63 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8717161 | 0.97 | MTNR1A (0.76) | MTNR1AMTNR1BMPOKMT2ACYP2D6 | |
| SCHEMBL8712198 | 0.90 | MPO (0.65) | MTNR1AMTNR1BMPOKMT2ACYP2D6 | |
| SCHEMBL1388848 | 0.88 | MTNR1A (0.61) | MTNR1AMTNR1BMPOCYP2D6KDM4E | |
| SCHEMBL7505689 | 0.86 | MTNR1A (0.92) | MTNR1AMTNR1BMPOKMT2ACYP2D6 | |
| SCHEMBL1129551 | 0.86 | MTNR1A (0.92) | MTNR1AMTNR1BMPOKMT2ACYP2D6 | |
| SCHEMBL8571512 | 0.86 | MTNR1A (0.92) | MTNR1AMTNR1BMPOKMT2ACYP2D6 | |
| SCHEMBL31036086 | 0.85 | MTNR1A (0.87) | MTNR1AMTNR1BMPOKMT2ACYP2D6 | |
| SCHEMBL5616635 | 0.84 | MTNR1A (0.85) | MTNR1AMTNR1BMPOKMT2ACYP2D6 | |
| SCHEMBL5616636 | 0.83 | MTNR1A (0.69) | MTNR1AMTNR1BMPOKMT2ACYP2D6 | |
| SCHEMBL1388844 | 0.83 | HTR1A (0.69) | MTNR1AMTNR1BKMT2ACYP2D6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5770610-A | ADMINISTERING R-(+)-N-(2-METHYL-2-(5-METHOXY-6-CHLOROINDOL-3-YL)ETHYL) ACETAMIDE | ELI LILLY AND COMPANY (US) | 1998-06-23 | — | — | US | disclosed |