Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MGLL | Q99685 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | REN | P00797 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL825414 | 0.97 | LMNA (0.63) | LMNAALDH1A1NPSR1TSHRMEN1 | |
| SCHEMBL638764 | 0.95 | LMNA (0.61) | LMNAALDH1A1NPSR1TSHRMEN1 | |
| SCHEMBL673623 | 0.95 | LMNA (0.61) | LMNAALDH1A1NPSR1TSHRMEN1 | |
| SCHEMBL149160 | 0.95 | LMNA (0.61) | LMNAALDH1A1NPSR1TSHRMEN1 | |
| SCHEMBL672047 | 0.95 | LMNA (0.61) | LMNAALDH1A1NPSR1TSHRMEN1 | |
| Carbamic Acid SCHEMBL6466030 | 0.91 | LMNA (0.57) | LMNAALDH1A1NPSR1TSHRMEN1 | |
| SCHEMBL375755 | 0.87 | FNTA (0.59) | LMNAALDH1A1NPSR1TSHRMEN1 | |
| SCHEMBL7397340 | 0.86 | LMNA (0.57) | LMNAALDH1A1NPSR1TSHRMEN1 | |
| SCHEMBL9547536 | 0.85 | LMNA (0.73) | LMNAALDH1A1NPSR1TSHRMEN1 | |
| SCHEMBL4018453 | 0.85 | LOXL2 (0.56) | LMNAALDH1A1NPSR1TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5714391-A | THERMALLY DECOMPOSING SULFUR-CONTAINING METAL ORGANIC COMPOUND | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1998-02-03 | — | — | US | disclosed |