Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
| ▸ | UBE2M | P61081 | 2/20 | 0.37 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8713638 | 0.88 | MEN1 (0.35) | PNMTCETPGAAGRIN2BSLC6A2 | |
| SCHEMBL8713286 | 0.86 | TP53 (0.44) | PNMTHTR2AHTR2CHTR2BCETP | |
| SCHEMBL8718439 | 0.85 | CYP2C19 (0.38) | SLC6A2SLC6A4 | |
| SCHEMBL8716625 | 0.85 | KIF11 (0.38) | PNMTSLC6A2SLC6A4 | |
| SCHEMBL8719228 | 0.84 | MAPT (0.44) | PNMTHTR2AHTR2CHTR2BGAA | |
| SCHEMBL8717503 | 0.80 | CBX7 (0.37) | SLC6A2SLC6A4 | |
| SCHEMBL8716595 | 0.78 | PPARG (0.38) | GRIN2B | |
| SCHEMBL8714096 | 0.77 | ADRB2 (0.38) | GAATSHRSLC6A2SLC6A4 | |
| SCHEMBL8715451 | 0.76 | TAAR1 (0.37) | GAA | |
| SCHEMBL8713653 | 0.75 | KIF11 (0.38) | PNMTGAASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |