Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | GLP1R | P43220 | 1/20 | 0.31 |
| ▸ | HEXA | P06865 | 1/20 | 0.30 |
| ▸ | HEXB | P07686 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8718664 | 0.83 | SELE (0.32) | — | |
| SCHEMBL30828905 | 0.83 | SELE (0.32) | — | |
| SCHEMBL29177511 | 0.76 | SELE (0.35) | OPRK1 | |
| SCHEMBL8175165 | 0.75 | KDM4E (0.31) | PDK2PDK4 | |
| SCHEMBL2115437 | 0.74 | — | — | |
| SCHEMBL2231375 | 0.73 | NOS2 (0.41) | LMNANPC1RAB9A | |
| SCHEMBL22436056 | 0.71 | — | — | |
| SCHEMBL8168067 | 0.69 | OPRK1 (0.38) | OPRK1GLP1R | |
| SCHEMBL10405310 | 0.69 | L3MBTL1 (0.31) | — | |
| SCHEMBL6719975 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708758-B1 | METHOD OF PREPARING 5-CHLORO-4-HYDROXYPYRIMIDINES, 2-CHLORENAMINES AS INTERMEDIATES IN THE METHOD, AND USE OF THE COMPOUNDS THUS PREPARED | HOECHST SCHERING AGREVO GMBH (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5523404-A | Process for preparing 5-chloro-4-hydroxypyrimidines | HOECHST SCHERING AGREVO GMBH (DE) | 1996-06-04 | — | — | US | disclosed |
| EP-0708758-A1 | METHOD OF PREPARING 5-CHLORO-4-HYDROXYPYRIMIDINES, 2-CHLORENAMINES AS INTERMEDIATES IN THE METHOD, AND USE OF THE COMPOUNDS THUS PREPARED | Hoechst Schering AgrEvo GmbH (DE) | 1996-05-01 | — | — | EP | disclosed |
| WO-1995001963-A1 | METHOD OF PREPARING 5-CHLORO-4-HYDROXYPYRIMIDINES, 2-CHLORENAMINES AS INTERMEDIATES IN THE METHOD, AND USE OF THE COMPOUNDS THUS PREPARED | HOECHST SCHERING AGREVO GMBH (DE) | 1995-01-19 | — | — | WO | disclosed |