Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8714257 | 0.78 | KIF11 (0.34) | TSHRKIF11MAPK1 | |
| SCHEMBL8719975 | 0.77 | ALDH1A1 (0.43) | TSHRKIF11MAPK1 | |
| SCHEMBL4544073 | 0.75 | KIF11 (0.52) | TSHRKIF11CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9408952 | 0.75 | TSHR (0.44) | TSHRKIF11CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8569751 | 0.72 | MAPK1 (0.41) | TSHRKIF11CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3663151 | 0.71 | MAPK1 (0.40) | KIF11MAPK1 | |
| SCHEMBL8718960 | 0.68 | CYP1A2 (0.47) | TSHRKIF11CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8570929 | 0.67 | TSHR (0.61) | TSHR | |
| SCHEMBL27338987 | 0.67 | PTPN1 (0.32) | TSHRKIF11CYP2C19MAPK1 | |
| SCHEMBL787874 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5744678-A | NICKEL COMPOUND, ORGANOPHOSPHORUS COMPOUND, ORGANOALUMINUM COMPOUND, CARBON-HALOGEN COMPOUNDS; CATALYST SELECTIVITY | NIPPON OIL CO., LTD. (JP) | 1998-04-28 | — | — | US | disclosed |
| EP-0758563-A1 | OLEFIN OLIGOMERIZATION CATALYST AND PROCESS FOR THE PREPARATION OF OLEFIN OLIGOMER USING IT | NIPPON OIL COMPANY, LTD. (JP) | 1997-02-19 | — | — | EP | disclosed |