Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 9/20 | 0.48 |
| ▸ | AR | P10275 | 8/20 | 0.48 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | SHBG | P04278 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9322215 | 0.82 | PGR (0.46) | PGRARNR3C2CYP19A1LMNA | |
| SCHEMBL8425073 | 0.82 | PGR (0.49) | PGRARNR3C2CYP19A1LMNA | |
| SCHEMBL6008256 | 0.79 | PGR (0.51) | PGRARNR3C2CYP19A1LMNA | |
| SCHEMBL13334668 | 0.77 | PGR (0.46) | PGRARNR3C2CYP19A1LMNA | |
| SCHEMBL7882963 | 0.76 | LMNA (0.62) | PGRARNR3C2LMNACYP3A4 | |
| SCHEMBL10601034 | 0.76 | PGR (0.50) | PGRARNR3C2CYP19A1LMNA | |
| SCHEMBL9472235 | 0.76 | LMNA (0.62) | PGRARNR3C2LMNACYP3A4 | |
| SCHEMBL11788940 | 0.75 | LMNA (0.69) | PGRARCYP19A1LMNACYP3A4 | |
| SCHEMBL10603383 | 0.75 | LMNA (0.69) | PGRARCYP19A1LMNACYP3A4 | |
| SCHEMBL8719020 | 0.73 | PGR (0.59) | PGRARNR3C2CYP19A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712264-A | 17-spiromethylene steroids | AKZO NOBEL N.V. (NL) | 1998-01-27 | — | — | US | disclosed |