Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 8/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 8/20 | 0.39 |
| ▸ | CNR2 | P34972 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1336531 | 0.84 | ALDH1A1 (0.46) | ALDH1A1TSHRCYP1A2CYP2D6GABRA1 | |
| SCHEMBL5009844 | 0.83 | ALDH1A1 (0.41) | ALDH1A1TP53TSHRCYP1A2CYP2D6 | |
| SCHEMBL8716923 | 0.82 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2CYP3A4TP53ALOX15 | |
| SCHEMBL9808921 | 0.81 | PTGS2 (0.49) | ALDH1A1SMN1; SMN2CYP3A4TP53ALOX15 | |
| SCHEMBL8719631 | 0.80 | SMN1; SMN2 (0.40) | ALDH1A1SMN1; SMN2CYP3A4TP53ALOX15 | |
| SCHEMBL584333 | 0.79 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2CYP3A4TP53ALOX15 | |
| SCHEMBL9242096 | 0.79 | XDH (0.46) | ALDH1A1SMN1; SMN2CYP3A4TP53ALOX15 | |
| SCHEMBL8721477 | 0.78 | SMN1; SMN2 (0.39) | ALDH1A1SMN1; SMN2CYP3A4TP53ALOX15 | |
| SCHEMBL8160137 | 0.78 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2CYP3A4TP53ALOX15 | |
| Water SCHEMBL28100235 | 0.77 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2CYP3A4TP53ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741438-A | Optically active biphenyl derivative, process for preparation thereof, liquid crystal composition containing the same as an effective component, and liquid crystal element using the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-04-21 | — | — | US | disclosed |
| EP-0395390-A1 | Optically active biphenyl derivative, process for preparation thereof, liquid crystal composition containing the same as effective component, and liquid crystal element using the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-10-31 | — | — | EP | disclosed |