SCHEMBL871980

SCHEMBL871980

[C]1C=COc2ccccc21

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.31
CRHBP P24387 2/20 0.31
CRHR2 Q13324 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2204951 1.00 LMNA (0.31) LMNACRHBPCRHR2SMN1; SMN2HTT
SCHEMBL5525170 0.67 ABCG2 (0.36) LMNACRHBPCRHR2SMN1; SMN2HTT
SCHEMBL30334802 0.67 LMNA (0.43) LMNACRHBPCRHR2SMN1; SMN2HTT
SCHEMBL1304032 0.67 CYP2A6 (0.31)
SCHEMBL121647 0.67 LMNA (0.43) LMNACRHBPCRHR2SMN1; SMN2HTT
Hydrochloric Acid SCHEMBL11520836 0.64 LMNA (0.41) LMNACRHBPCRHR2SMN1; SMN2HTT
SCHEMBL219574 0.64
SCHEMBL996383 0.62
Cyclohexane SCHEMBL23674790 0.60 SMN1; SMN2 (0.43) LMNACRHBPCRHR2SMN1; SMN2HTT
SCHEMBL577897 0.58 MAOA (0.42) LMNACRHBPCRHR2SMN1; SMN2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230228684-A1 METHODS AND SYSTEMS FOR SPATIALLY IDENTIFYING ABNORMAL CELLS LUMICELL, INC. (US) 2023-07-20 US disclosed
US-11592396-B2 Methods and systems for spatially identifying abnormal cells LUMICELL, INC. (US) 2023-02-28 US disclosed
EP-2618849-B1 MULTIVALENT FLUORESCENT PROBES CALIPER LIFE SCIENCES INC (US) 2020-10-21 EP disclosed
EP-3695853-A1 MOLECULAR IMAGING PROBES AND THEIR COMPOSITIONS Lumicell Diagnostics, Inc. (US) 2020-08-19 EP disclosed
US-20200225160-A1 METHODS AND SYSTEMS FOR SPATIALLY IDENTIFYING ABNORMAL CELLS LUMICELL, INC. (US) 2020-07-16 US disclosed
EP-2646057-B1 METHODS AND SYSTEMS FOR SPATIALLY IDENTIFYING ABNORMAL CELLS LUMICELL INC (US) 2020-03-18 EP disclosed
US-9289515-B2 Multivalent fluorescent probes CALIPER LIFE SCIENCES (US) 2016-03-22 US disclosed
US-20160025632-A1 METHODS AND SYSTEMS FOR SPATIALLY IDENTIFYING ABNORMAL CELLS LUMICELL, INC. (US) 2016-01-28 US disclosed
US-9155471-B2 Methods and systems for spatially identifying abnormal cells Lumicell, Inc'. (US) 2015-10-13 US disclosed
US-20150209450-A1 MULTIVALENT FLUORESCENT PROBES PERKINELMER INC (US) 2015-07-30 US disclosed
US-20110104071-A1 METHODS AND SYSTEMS FOR SPATIALLY IDENTIFYING ABNORMAL CELLS LUMICELL DIAGNOSTICS, INC. (US) 2011-05-05 US disclosed
US-20110021908-A1 METHODS AND SYSTEMS FOR SPATIALLY IDENTIFYING ABNORMAL CELLS LUMICELL DIAGNOSTICS, INC. (US) 2011-01-27 US disclosed
WO-2010138738-A1 METHODS AND SYSTEMS FOR SPATIALLY IDENTIFYING ABNORMAL CELLS LUMICELL DIAGNOSTICS, INC. (US) 2010-12-02 WO disclosed
US-20050214221-A1 Optical imaging probes VISEN MEDICAL, INC. (US) 2005-09-29 US disclosed
EP-1485716-A1 OPTICAL IMAGING PROBES Visen Medical, Inc. (US) 2004-12-15 EP disclosed
EP-1428858-A1 Hydrophilic marker dyes based on benzopyrylo-polymethines Dyomics GmbH (DE) 2004-06-16 EP disclosed
EP-1273584-B1 2- or 4-Chromenyliden based merocyanines and use thereof DYOMICS GMBH (DE) 2004-02-18 EP disclosed
WO-2003079015-A1 OPTICAL IMAGING PROBES VISEN MEDICAL, INC. (US) 2003-09-25 WO disclosed
EP-1273584-A1 2- or 4-Chromenyliden based merocyanines and use thereof Dyomics GmbH (DE) 2003-01-08 EP disclosed
EP-1273584-A1 2- or 4-Chromenyliden based merocyanines and use thereof Dyomics GmbH (DE) 2003-01-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150209450-A1 MULTIVALENT FLUORESCENT PROBES CHERP, CD2BP2, DNM1L LMNA 2386/4885CRHBP 2578/4885CRHR2 4041/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.