Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 8/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 8/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.36 |
| ▸ | PDE4A | P27815 | 5/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9571268 | 0.78 | HRH3 (0.45) | HRH3PDE3BPDE3APDE4BPDE4A | |
| SCHEMBL8714845 | 0.77 | HRH3 (0.44) | HRH3PDE3BPDE3APDE4BPDE4A | |
| SCHEMBL8720034 | 0.76 | HDAC8 (0.42) | HRH3GRIA2 | |
| SCHEMBL5184219 | 0.75 | HRH3 (0.46) | HRH3PDE3BPDE3APDE4BPDE4A | |
| SCHEMBL6401437 | 0.74 | PDE3B (0.42) | HRH3PDE3BPDE3APDE4BPDE4A | |
| SCHEMBL11366945 | 0.74 | HRH3 (0.42) | HRH3PDE3BPDE3APDE4BPDE4A | |
| SCHEMBL8303766 | 0.73 | PDE3B (0.51) | PDE3BPDE3APDE4BPDE4APDE4C | |
| SCHEMBL5183009 | 0.73 | TDP2 (0.41) | HRH3PDE3BPDE3APDE4B | |
| SCHEMBL5335003 | 0.72 | HRH3 (0.46) | HRH3PDE3BPDE3APDE4BMAPT | |
| SCHEMBL6400233 | 0.72 | PDE4B (0.52) | HRH3PDE3BPDE3APDE4BPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739132-A | ENDOTHOXIN SHOCK; NEPHRITIS | TANABE SEIYAKU CO., LTD. (JP) | 1998-04-14 | — | — | US | disclosed |
| EP-0579059-A1 | Pyridazinone derivatives and processes for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1994-01-19 | — | — | EP | disclosed |