Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.41 |
| ▸ | PPARA | Q07869 | 7/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12788341 | 0.79 | AKT1 (0.43) | PPARGPPARASMN1; SMN2CYP3A4HTT | |
| SCHEMBL3678445 | 0.76 | TSHR (0.45) | SMN1; SMN2CYP3A4HTTTSHRMEN1 | |
| SCHEMBL3469555 | 0.76 | ALDH1A1 (0.40) | SMN1; SMN2MEN1LMNAKMT2A | |
| SCHEMBL16560397 | 0.76 | LTA4H (0.52) | MEN1KMT2A | |
| SCHEMBL1291772 | 0.75 | LMNA (0.42) | PPARASMN1; SMN2CYP3A4HTTLMNA | |
| SCHEMBL12847098 | 0.74 | PPARG (0.50) | PPARGPPARAHCRTR2TSHRLMNA | |
| SCHEMBL2799777 | 0.74 | TDP1 (0.52) | HTTTSHRMEN1LMNAALOX15 | |
| SCHEMBL5724513 | 0.74 | ALDH1A1 (0.40) | SMN1; SMN2 | |
| SCHEMBL8720374 | 0.74 | HCRTR2 (0.41) | PPARGPPARAHTTHCRTR2TSHR | |
| SCHEMBL29839768 | 0.74 | ICMT (0.44) | PPARGPPARATSHRMEN1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0839828-A1 | Building blocks for DNA/PNA-Cooligomer | BAYER AG (DE) | 1998-05-06 | — | — | EP | disclosed |