Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL316761 | 0.93 | TGFBR1 (0.32) | TGFBR1 | |
| SCHEMBL4391034 | 0.91 | — | — | |
| SCHEMBL4393922 | 0.82 | KDM4E (0.31) | — | |
| Sulfuric Acid SCHEMBL6211665 | 0.78 | TGFBR1 (0.36) | TGFBR1 | |
| Sulfuric Acid SCHEMBL6812276 | 0.76 | ZDHHC20 (0.47) | — | |
| Sulfuric Acid SCHEMBL11210945 | 0.76 | EPHX1 (0.41) | TGFBR1 | |
| SCHEMBL11695754 | 0.75 | TGFBR1 (0.32) | TGFBR1 | |
| SCHEMBL31304716 | 0.74 | SIGMAR1 (0.40) | TGFBR1 | |
| SCHEMBL5539476 | 0.74 | TGFBR1 (0.34) | TGFBR1 | |
| Sulfuric Acid SCHEMBL3381903 | 0.73 | EPHX1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5783533-A | COPOLYMER CONTAINING ACRYLIC ACID TYPE GROUPS, ACRYLIC, VINYL, OR ALLYL MONOMERS WITH PENDANT AMMONIUM OR SULFONIUM GROUPS, POSSIBLY WITH POLYOXYALKYLENE ETHER SECTION, RHEOLOGY MODIFIERS | COATEX S.A. (FR) | 1998-07-21 | — | — | US | claimed |
| US-5783533-A | COPOLYMER CONTAINING ACRYLIC ACID TYPE GROUPS, ACRYLIC, VINYL, OR ALLYL MONOMERS WITH PENDANT AMMONIUM OR SULFONIUM GROUPS, POSSIBLY WITH POLYOXYALKYLENE ETHER SECTION, RHEOLOGY MODIFIERS | COATEX S.A. (FR) | 1998-07-21 | — | — | US | disclosed |