Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.69 |
| ▸ | TSHR | P16473 | 5/20 | 0.69 |
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | DRD4 | P21917 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | HTR1A | P08908 | 3/20 | 0.61 |
| ▸ | HTR7 | P34969 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1644843 | 0.87 | L3MBTL1 (0.79) | MEN1KMT2ANPSR1CYP1A2CYP2C9 | |
| SCHEMBL8722756 | 0.86 | MAPT (0.72) | MEN1KMT2AALDH1A1TSHRMAPT | |
| SCHEMBL14207957 | 0.82 | MAPT (0.66) | MEN1KMT2ANPSR1CYP1A2CYP2C9 | |
| SCHEMBL5796341 | 0.81 | MAPT (0.65) | MEN1KMT2ANPSR1CYP1A2CYP2C9 | |
| SCHEMBL977710 | 0.80 | ALDH1A1 (0.65) | MEN1KMT2ANPSR1CYP1A2CYP2C9 | |
| SCHEMBL8443672 | 0.79 | ALDH1A1 (0.65) | MEN1KMT2ANPSR1CYP1A2CYP2C9 | |
| SCHEMBL17946603 | 0.78 | CACNA1G (0.72) | MEN1KMT2ANPSR1ALDH1A1TSHR | |
| SCHEMBL4005507 | 0.78 | DRD4 (1.00) | MEN1KMT2AALDH1A1TSHRMAPT | |
| SCHEMBL5796448 | 0.78 | KDM4E (0.70) | MEN1KMT2AALDH1A1TSHRMAPT | |
| SCHEMBL4004151 | 0.78 | GAA (0.59) | MEN1KMT2ANPSR1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998042692-A1 | PIPERAZINES DERIVED FROM CYCLIC AMINES, PREPARATION AND APPLICATION THEREOF AS MEDICINES | PIERRE FABRE MEDICAMENT (FR) | 1998-10-01 | — | — | WO | disclosed |